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Image Search Results
Journal: Cell
Article Title: Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in rhesus macaques coincides with anamnestic antibody response in the lung
doi: 10.1016/j.cell.2021.12.002
Figure Lengend Snippet: mRNA-1273 provides durable protection in the lower airway from B.1.617.2 (A and B) Representative images of lung samples 7 days after B.1.617.2 challenge from 4 NHPs that received mRNA-1273 (A) or mRNA control (B). Top row, detection of SARS-CoV-2 antigen by immunohistochemistry with a polyclonal anti-N antibody. Antigen-positive foci are marked by red arrows. Bottom row, hematoxylin and eosin (H&E) staining illustrating the extent of inflammation and cellular infiltrates. Images at 10× magnification with black bars for scale (100 μm). (C) SARS-CoV-2 antigen and inflammation scores in the left cranial (Lc) lobe, right middle (Rmid) lobe, and right caudal (Rc) lobe of the lungs 7 days after B.1.617.2 challenge. Antigen scoring legend: –, no antigen detected; +/−, rare to occasional foci; +, occasional to multiple foci; ++, multiple to numerous foci; +++, numerous foci. Inflammation scoring legend: –, minimal to absent inflammation; +/−, minimal to mild inflammation; +, mild to moderate inflammation; ++, moderate to severe inflammation; +++, severe inflammation. Horizontal rows correspond to individual NHPs depicted above (A and B).
Article Snippet:
Techniques: Control, Immunohistochemistry, Staining
Journal: Cell
Article Title: Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in rhesus macaques coincides with anamnestic antibody response in the lung
doi: 10.1016/j.cell.2021.12.002
Figure Lengend Snippet:
Article Snippet:
Techniques: Labeling, Virus, Neutralization, Recombinant, Transfection, Staining, Multiplex Assay, Diagnostic Assay, Software